Consumer Information for: PMS-DILTIAZEM CD

As with most medicines, interactions with other drugs are possible. Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines.

Additional monitoring of your dose or condition may be needed if you are taking other drugs.

The following may interact with pms-DILTIAZEM CD:

• Antifungal medications with a name ending in azole;
• Medications used to control the immune system such as cyclosporine;
• Certain antibiotics should not be taken with pms-DILTIAZEM CD such as erythromycin, rifampin. Check with your pharmacist if not sure;
• Sleeping pills such as benzodiazepines (midazolam, triazolam);
• Other blood pressure medications: alpha antagonists, beta-blockers;
• Heart medications: Amiodarone, digoxin, digitalis, flecainide, nifedipine, propafenone, quinidine, verapamil;
• anaesthetics;
• Lithium and imipramine used for some types of mental illness;
• Drugs that dilate the blood vessels: short and long acting nitrates;
• Medications used to control seizures:
• carbamazepine, phenobarbital, phenytoin;
• Warfarin used as anticoagulant;
• Cholesterol lowering medications: statins;
• Theophylline used for breathing problems;
• Terfenadine or ranitidine used for allergies;
• Medications used to control stomach ulcers such as cimetidine will increase the effects of pms-DILTIAZEM CD;
• Multivitamins with minerals (calcium-containing products);
• Drugs to treat inflammation: corticosteroids, methylprednisolone;
• Dantrolene used for severe muscle spasms or severe fever.
• Acetylsalicylic acid (Aspirin)
• X-Ray contrast agents.

Alcohol may cause low blood pressure and dizziness when you go from lying or sitting to standing up. This can especially occur after the first dose and when the dose is increased. Tell your doctor if you experience dizziness, light-headedness, fainting, decreased blood pressure or increased heart rate.

Grapefruit juice when consumed too often while taking pms-DILTIAZEM CD may cause headache, irregular heartbeat, edema (swelling), unexplained weight gain, and chest pain. Tell your doctor if this happens to you. Your doctor may recommend that grapefruit juice be avoided if this happens to you.