Consumer Information for: ADDNUTRIV
Consumer Information
Information about the product including what the product is used for, dosage, warnings, proper use and side effects. This summary will not tell you everything about the product. Contact your healthcare professional if you have any questions about the product.
What the medication is used for
- Addnutriv is used along with other products that contain nutrients that are given to you through an infusion into your vein.
- It contains trace elements which are nutrients that your body needs in very small amounts.
- It is given to meet your body’s trace element needs when you cannot eat normally.
- It is used in adults only.
- It prevents reduction of trace elements in your body and feeling unwell due to their lack.
What it does
Addnutriv gives you the trace elements that your body needs. These are given directly into your blood. The trace elements are then used by your body for many different functions.
When it should not be used
- are allergic to Addnutriv.
- are allergic to any of the ingredients in Addnutriv or to a component of the container.
- have a biliary obstruction, a condition where your bile ducts are blocked.
- have Wilson’s disease, a genetic disorder where your body stores too much copper.
- have hemochromatosis, a condition where your body stores too much iron.
What the medicinal ingredient is
| Chromium | (as Chromic chloride hexahydrate) |
| Copper | (as Cupric chloride dihydrate) |
| Iron | (as Ferric chloride hexahydrate) |
| Manganese | (as Manganese chloride tetrahydrate) |
| Iodine | (as Potassium iodide) |
| Fluoride | (as Sodium fluoride) |
| Molybdenum | (as Sodium molybdate dihydrate) |
| Selenium | (as Sodium selenite) |
| Zinc | (as Zinc chloride) |
What the non-medicinal ingredients are
Non-medicinal ingredients: hydrochloric acid water for injection and xylitol.
What dosage form it comes in
As a solution that contains:
| Chromium | 10 micrograms / 10 mL |
| Copper | 380 micrograms / 10 mL |
| Iron | 1100 micrograms / 10 mL |
| Manganese | 55 micrograms / 10 mL |
| Iodine | 130 micrograms / 10 mL |
| Fluoride | 950 micrograms / 10 mL |
| Molybdenum | 19 micrograms / 10 mL |
| Selenium | 79 micrograms / 10 mL |
| Zinc | 5000 micrograms / 10 mL |
Warnings and precautions
- have kidney problems.
- have liver problems.
- have a condition called cholestasis where bile does not flow properly from the liver to the intestine.
- are taking an iron supplement by mouth in addition to Addnutriv. Your doctor will make sure that too much iron does not collect in your body.
- are pregnant.
- are breast-feeding.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements, or other medicines.
Interactions with this medication
- Nutritional supplements that contain molybdenum.
- Vitamin C supplement that is given to you through an infusion into your vein
Proper use of this medication
- Addnutriv will be given to you by a healthcare professional.
- Your healthcare professional will make sure that Addnutriv is prepared correctly before it is given to you.
- It will first be mixed with another solution before it is given to you.
- It will then be infused slowly into your vein.
- It will usually be infused over a period of 8 hours.
- Follow all instructions given to you by your health care professional.
Usual Dose
- Your doctor will decide how much Addnutriv you will receive.
- The usual dose is 10 mL of Addnutriv a day.
- Your doctor may give you a lower dose of Addnutriv if you have:
- kidney problems
- liver problems
- or if you have a condition called cholestasis where bile does not flow properly from the liver to the intestine
Overdose
If you think you have taken too much Addnutriv, contact your healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms.
Missed Dose
Side effects and what to do about them
These are not all the possible side effects that you may feel when taking Addnutriv. If you experience any side effects not listed here, contact your healthcare profession
Addnutriv is used along with other products that contain nutrients. Serious side effects may include:
| Symptom / effect | Talk to your healthcare professional Only if severe | Talk to your healthcare professional In all cases | Stop taking drug and get immediate medical help |
|---|---|---|---|
| Very Rare | |||
| Allergic Reaction: difficulty breathing, difficulty swallowing, fever, hives, itchy skin, loss of consciousness, rash, swelling of your tongue, throat or face. | ✔ | ||
| Digestive system problems: diarrhea, nausea, vomiting. | ✔ | ||
| General: chills, pain, chest discomfort and pain, tiredness | ✔ | ||
| Heart problems: heart beating too hard or too fast, skipping a beat, or fluttering, irregular heartbeats. | ✔ | ||
| Infections: body aches and pains, chills, burning or pain with urination, coughing, fatigue, fever, new onset of pain, not feeling well, any unusual discharge from your body | ✔ | ||
| Injection site reactions: pain, redness or swelling at the injection site. | ✔ | ||
| Kidney problems: back and abdominal pain, change in the colour of urine (pale or dark), decrease in amount of urine produced, pain or discomfort when urinating, swelling of the legs and ankles. | ✔ | ||
| Liver problems: abdominal pain, dark urine, fatigue, loss of appetite, nausea, swollen abdomen, vomiting, weakness, yellowing of the skin or eyes (jaundice). | ✔ | ||
| Muscle problems: back pain, muscle cramps, pain or twitching | ✔ | ||
| Lung problems: blue tint to the face and lips, shortness of breath, too much fluid in lung. | ✔ | ||
| Skin problems: cold sweat, redness, sweating. | ✔ | ||
| Blood clot in a vein: pain, tenderness, redness, warmth or swelling of a body area, swelling or hardening of a vein near the surface of the skin. | ✔ | ||
| Low blood pressure | ✔ | ||
Addnutriv can cause abnormal blood test results. Your doctor may perform blood tests and will interpret the results. If you receive Addnutriv for more than 4 weeks, your doctor will check the levels of manganese in your blood
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.
How to store
Store at room temperature (15°C to 30°C). Do not freeze. No special precautions for storage of the unopened plastic container.
Keep out of reach and sight of children.
Reporting side effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/healthcanada/services/drugs-health-products/medeffectcanada/adverse-reaction-reporting.html) for information on how to report online, by mail or by fax; or
- Calling toll-free at 1-866-234-2345.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
More information
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website (https://healthproducts.canada.ca/dpd-bdpp/index-eng.jsp); the manufacturer’s website (https://www.freseniuskabi.com/en-ca/), or by calling 1-877-821-7724.
This leaflet was prepared by:
Fresenius Kabi Canada Ltd.
165 Galaxy Blvd, Suite100
Toronto, ON M9W 0C8
Fresenius Kabi is a registered trademark of Fresenius SE, Addnutriv is a trademark of Fresenius Kabi AG
Date of Revision: March 31, 2020
Related Drug Products
| Product name | DIN | Company name | Active ingredient(s) & strength |
|---|---|---|---|
| AURO-CEPHALEXIN | 02497743 | AURO PHARMA INC | CEPHALEXIN (CEPHALEXIN MONOHYDRATE) 125 MG / 5 ML |
| AURO-CEPHALEXIN | 02497751 | AURO PHARMA INC | CEPHALEXIN (CEPHALEXIN MONOHYDRATE) 250 MG / 5 ML |